QTOF mass spectrometer coupled with Dionex Ultimate 3000 capillary liquid chromatography.
The resolution is 20,000-40,000 in both MS and MS/MS.
Mass precision is <5ppm.
Capillary columns with a diameter of 300µm are used on this apparatus, ensuring a good compromise between robustness and sensitivity (100fmol).
High resolution qualitative and quantitative analyses in capillary LC-MS/MS.
This apparatus is particularly valuable when working on complex mixtures of molecules. It is possible to identify proteins in both DDA and DIA modes.
We use it for clinical research programmes on peptide biomarkers